Discussions
Introduction to agility training for dogs.
Agility training for dogs builds fitness, focus, and a strong bond between dog and owner.
Safety & Toxicology
We provide a wide range of research chemicals and biochemicals including inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities and metabolites, APIs, natural compounds, ADCs, stem cell molecule and chiral compounds. Details about Computational Toxicology
Mark out the Important factor of Power Bi
Power BI is a powerful business intelligence and data visualization tool developed by Microsoft. Its importance in today's business landscape cannot be overstated for several key reasons:
LBP Research
Next-Generation Probiotics (NGPs) refer to advanced or engineered strains of microorganisms developed to provide targeted and enhanced health benefits beyond those offered by traditional probiotics like Lactobacillus and Bifidobacterium. These probiotics are derived from novel bacterial species, synthetically engineered strains, or microbiome-derived microorganisms, aiming to address specific medical and therapeutic needs.
Antibody-drug conjugates
Antibody-drug conjugates (ADCs) have shown great promise as targeted cancer therapies, but their plasma stability is a crucial factor that can influence their therapeutic efficacy and safety. Plasma stability refers to the ability of an ADC to maintain its structural integrity and functional potency while circulating in the bloodstream. Poor plasma stability can lead to premature release of the cytotoxic drug from the antibody, potentially causing off-target effects or reducing the overall therapeutic index. To ensure optimal plasma stability, ADCs must be designed with robust linkers that can withstand the harsh conditions of the bloodstream, such as enzymatic degradation or chemical instability. This involves careful selection of linker chemistry, stability testing in various plasma environments, and monitoring of the ADC’s pharmacokinetics. Improved plasma stability not only enhances the therapeutic benefit of ADCs but also reduces the risk of adverse side effects, making it a critical parameter in the development of safe and effective ADC therapies.
Antibody Isotype Switching
As a senior expert in antibody development, Creative Biolabs owns lots of scientists who are proficient in non-IgG therapeutic antibody production, engineering, and application. Our professional scientists are pleased to provide the custom non-IgG antibody isotype switching service against diverse disease biomarkers to diagnose and treat related diseases efficiently. We believe our first-class services will fit your needs in your most critical research requirements.
ELISA for IVD Development
Enzyme-linked immunosorbent assays (ELISAs) can be used to detect antigens, antibodies, and haptens. It is a highly sensitive tool in in vitro diagnostics (IVD). Supported by an experienced team of scientists working with the latest molecular diagnosis technology, Creative Biolabs provides a variety of ELISA testing services to meet your testing needs for different samples. We also provide the development services of different types of ELISA kits to support scientific research for customers all over the world.
Human OVCAR-8 Tumor Cell Line
The OVCAR-8 cell line is a human ovarian carcinoma cell line derived from the ascitic fluid of a patient with ovarian adenocarcinoma. It is commonly used in cancer research, particularly for studying ovarian cancer biology, chemoresistance, and therapeutic testing. Here are some key features of the OVCAR-8 cell line:
Half-Life Strategies in Supporting the Development of Protein Therapeutics
Therapeutics based on macromolecular proteins and peptides have successfully been efficiently applied to treat serious human diseases. With the development of biotechnologies, a great number of authorized protein therapeutics and drug products have been utilized in clinical research over the last few decades. However, the main issue that needs to be resolved currently for protein therapeutics is the short half-lives caused by fast degradation in serum and quick elimination during clinical application due to enzymatic degradation, renal clearance, liver metabolism, and immunogenicity.
Ribosomes: Orchestrators of Cellular Harmony and Enigmas in Disease
Cells, the microscopic building blocks of the human body, operate like a sophisticated symphony orchestra, finely orchestrating numerous life processes. In this diminutive yet intricate world, ribosomes function as conductors, guiding the synthesis of proteins—the essential constituents of life. However, disruptions in ribosomal function are frequently linked to cellular dysfunction, intimately intertwining them with the onset and progression of various diseases.